coach bags sale report,Writing in Cancer Prevention
Research, they said oestrogen helped pre-cancerous cells move and divide by triggering the
activity of an enzyme.
Head and neck cancer, including mouth, tongue and throat cancers, affects up to 9,000 people
every year in the UK.
UK experts said the work was interesting, but at an early stage.
There has been an increase in diagnoses of head and neck cancers in younger women over the last
10 years, but most cases are still seen in men aged 50-74.
Smoking and drinking alcohol are known risk factors.
Cell death
mens prada sunglassesThe researchers at Fox Chase Cancer Center carried out lab tests which showed oestrogen triggers
the activity of CYP1B1.
However, activity was only seen in pre-cancerous cells, and not in healthy cells or ones that had
become cancerous.
When the research team blocked the activity of the enzyme, pre-cancerous cells were less able to
move and divide.
mens prada shoesDr Margie Clapper, who led the research, said: "CYP1B1 could be a wonderful target in pre-
cancerous lesions of the head and neck, because by attacking it, we might stop these lesions from
progressing or moving to a more advanced stage."
Dr Kat Arney, a spokeswoman for Cancer Research UK, said: "This research has been carried out
using cancer cells grown in the lab, and while it's an interesting finding, more work is needed
before we know for sure what role oestrogen plays in head and neck cancers